Zotonic, there's a new asynchronous, next-gen content management system in town.Move over
Calipso is a CMS written in Node.js and using MongoDB as its database. According to the project website, Calipso doesn't feature caching yet but can support around 180 hits a second. You can find it in Github here.
This is the first full fledged Node.js-based CMS we've seen, though Tim Caswell did build a blogging engine based on Node.js and Git called Wheat.
Calipso was created by London-based developer Clifton Cunningham. Cunningham has worked on several Node.js and Drupal project in the past.